Reactome Protein Interaction Network
A Reactome biological pathway database dataset of 6,327 nodes and 147,547 edges, collected by Reactome consortium. Each record contains directed: False, weighted: False, signed: False. Protein-protein interaction network from the Reactome pathway database — large-scale biological network.. Suitable for biological network analysis, community detection, protein interaction research.
Cite this dataset at
reactome.echo.directory
Analytics
The full graph has 6,327 nodes; this view shows the 1,000-node sample the pipeline drew for display. Node size is centrality, colour is community.
Computed over the full corpus.
Record
- Catalog key
reactome- Authors
- Joshi-Tope, G.
- Year
- 2004
- Source paper
- Reactome: a knowledgebase of biological pathways
- DOI / arXiv
- 10.1093/nar/gki072
- License
- CC BY-SA 2.0 Germany (as stated by KONECT) (LicenseRef-CC-BY-SA-2.0-DE)
- Records
- 6,327
- Nodes
- 6,327
- Edges
- 147,547
- Nodes are
- protein
- Edges are
- interaction
- Attributes
- nodes have no attributes; edges have no attributes
- Languages
- en
- Collected
- 2010 (2010s)
- Tasks
- From the graph: link prediction, community detection
Provenance
- Originally published at
- https://konect.cc/networks/reactome/ unverified
- Hosted copy
- Mirrored on echo.directory on 2026-10-02, 373.1 KB across 1 files. Checksums in MANIFEST.json.
Citations
Reactome: a knowledgebase of biological pathways
G. Joshi-Tope, M. Gillespie, I. Vastrik, Peter D'Eustachio, E. Schmidt
Journal Article · Nucleic Acids Res. · 2004
Cited by
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K. Michailidou, S. Lindström et al. · Nature · 2017 · cited 1.4K× - The Reactome Pathway Knowledgebase 2024
M. Milacic, Deidre Beavers et al. · Nucleic Acids Research · 2023 · cited 1.3K×
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Citation data from Semantic Scholar, retrieved 2026-10-19.
How to cite
BibTeX
@misc{echo2026,
title = {ECHO: Exploratory Compendium of Humanity Online},
author = {Switzer, Braden and Zafarani, Reza},
year = {2026},
url = {https://echo.directory},
note = {Syracuse University}
}
@article{Joshi_Tope_2004,
title = {Reactome: a knowledgebase of biological pathways},
volume = {33},
issn = {1362-4962},
url = {http://dx.doi.org/10.1093/nar/gki072},
doi = {10.1093/nar/gki072},
number = {Database issue},
journal = {Nucleic Acids Research},
publisher = {Oxford University Press (OUP)},
author = {Joshi-Tope, G.},
year = {2004},
month = Dec,
pages = {D428–D432}
} APA
Switzer, B., & Zafarani, R. (2026). ECHO: Exploratory Compendium of Humanity Online [Data repository]. Syracuse University. https://echo.directory
Joshi-Tope, G. (2004). Reactome Protein Interaction Network [Data set]. https://doi.org/10.1093/nar/gki072
MLA
Switzer, Braden, and Reza Zafarani. ECHO: Exploratory Compendium of Humanity Online. Syracuse University, 2026, echo.directory.
Joshi-Tope, G. Reactome Protein Interaction Network. 2004, doi.org/10.1093/nar/gki072.